洪泽璇博士，副研究员，硕士生导师。2022年于南方医科大学获得临床医学专业博士学位，2022年至2025年作为深圳市妇幼保健院及深圳先进院联合培养博士后进行科研训练；2025年7月起就职于深圳先进院。

主要从事AAV载体优化改造及帕金森病神经环路靶向调控研究。

神经科学

1.  Yefei Chen#; Zexuan Hong#; Jingyi Wang; Kunlin Liu; Jing Liu; Jianbang Lin; Shijing Feng; Tianhui Zhang; Liang Shan; Taian Liu; Pinyue Guo; Yunping Lin; Tian Li; Qian Chen; Xiaodan Jiang; Anan Li; Xiang Li; Yuantao Li; Jonathan J. Wilde; Jin Bao*; Ji Dai*; Zhonghua Lu*. Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model. Cell, 2023, 186(24): 5394-5410. (2023).
2.  Zexuan Hong#; Jun Cao#; Dandan Liu#; Maozhu Liu; Mengyuan Chen; Fanning Zeng; Zaisheng Qin*; Jigang Wang*; Tao Tao*. Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke. Journal of pharmaceutical analysis,2023, 13(2), 156–169. (2023).
3.  Qi Zhang#; Ruiqi Wang#; Liang Zhang#; Mengqi Li; Xiaoyang Lu; Yixuan Tian; Jianbang Lin; Yefei Chen; Yuantao Li; Jun Cao; Qiang Wu*; Jinhui Wang*; Zhonghua Lu; Zexuan Hong* ; A humanized Gs-coupled DREADD for circuit and behavior modulation. Frontiers in cellular neuroscience, 19, 1577117. (2025).
4.  Fanning Zeng#; Jun Cao#; Zexuan Hong#; Yujun Liu; Jie Hao; Zaisheng Qin*; Xin Zou*; Tao Tao* ; Single-cell analyses reveal the dynamic functions of Itgb2+ microglia subclusters at different stages of cerebral ischemia-reperfusion injury in transient middle cerebral occlusion mice model, Frontiers in Immunology, 2023, 14.(2023).
5.   Yefei Chen#; Zexuan Hong#; Ting Yan; Yuyuan Zhu; Jianbang Lin; Taian Liu; Ming Guo; Mengqi Li; Shijing Feng; Ronghui Li; Jianqing Zhang; Siyang Chen; Yi Yang; Yuantao Li*; Zhonghua Lu*. Protocol for chemogenetic activation of basal ganglia D1-MSNs and behavioral assessments in a primate Parkinson's disease model. STAR protocols vol. 5,4 (2024): 103470.(2024).

以第一和通讯作者（含共一）身份在Cell，Journal of pharmaceutical analysis、Frontiers In Cellular Neuroscience，Frontiers in Immunology等杂志发表文章,申请专利2项。主持中国博士后基金1项，国家自然科学基金青年科学基金项目1项。其中，脑疾病环路靶向基因治疗技术入选2023年度”中国生命科学十大进展”(第五完成人)。